Rate My Professor Jean-Pierre Levesque

Levesque has obtained over $8 million in competitive grants, including NHMRC Research Fellowships (2018–2022, 2013–2017), Project Grants on endothelial selectins in stem cell fate (2017–2020), recipient bone marrow macrophages in transplantation (2016–2019), hypoxia sensing in mobilization (2014–2016), and IDEAS Grants such as Mechanisms and first prophylactic treatments of neurogenic heterotopic ossifications (2025–2028) and Discovering mechanisms of neurogenic heterotopic ossifications (2020–2024). He has principal-supervised PhD theses including Role of infections and gut microflora in neurogenic heterotopic ossifications (2023), The Role of Macrophages in Acute Myeloid Leukaemia (2021), and Role of Bone Marrow Macrophages in Regulating Haematopoiesis (2015). His contributions include clinical introduction of Plerixafor for stem cell mobilization in multiple myeloma and lymphoma, guidelines in 'How I treat patients who mobilize hematopoietic stem cells poorly' (Blood, 2011), and discoveries of bone marrow niche proteins causing leukemia chemotherapy resistance, leading to preclinical sensitization models and clinical trials with higher AML remission rates. He holds four patents, edits an international haematology journal, and performs NHMRC peer review. Highly cited publications encompass 'Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs' (Blood, 2010), 'Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide' (Journal of Clinical Investigation, 2003), 'Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance' (Nature Medicine, 2012), and 'G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow' (Blood, 2005). Recent articles include 'A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury' (Cell Reports Medicine, 2024) and 'Role of endocrinal dysregulations in traumatic heterotopic ossification pathogenesis' (Current Opinion in Endocrinology, Diabetes and Obesity, 2025).