Rate My Professor Jeffrey Grice

Grice's research centers on transdermal drug absorption, including the targeting of topically applied drugs to deep or superficial tissues below the skin. He investigates chemical properties of solutes that influence local and systemic uptake and distribution. A major theme is nanotechnology, involving nanoemulsions and nanoparticulates as drug carriers, alongside nanotoxicology assessments of skin-applied materials such as nano-sunscreens, quantum dots, gold, and silver nanoparticles. His methodologies incorporate non-invasive imaging via multiphoton and confocal microscopy to monitor penetration and metabolic responses. Grice is co-author of 108 peer-reviewed research articles and 9 research book chapters, with a ResearchGate profile documenting 179 publications and 7,712 citations. Key publications include 'Mechanistic Modelling of Lidocaine and Prilocaine Absorption from EMLA Cream upon Topical Application using Physiologically Based Pharmacokinetic Modelling' (2025), 'Effect of “In Use” Administration on Topical Product Metamorphosis and Skin Permeation of Acyclovir Creams: Implications for Bioequivalence' (2024), 'In vitro screening of topical formulation excipients for epithelial toxicity in cancerous and non-cancerous cell lines' (2023), and 'Human Skin Drug Metabolism: Relationships between Methyl Salicylate Metabolism and Esterase Activities in IVPT Skin Membranes' (2023). He currently leads NHMRC-funded work on specific targeting of nanosystems by cutaneous delivery and a project on regional chemotherapeutic treatment using fluorescent anti-melanoma agents funded by the Princess Alexandra Hospital Research Foundation. Grice supervises PhD students and fosters collaborations across university groups, government, and industry.