Engineer in Homologous Recombination (F/M)

Offer Description

The hosting structure

Institut Curie Research Center is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Context

The laboratory

The successful candidate will join the Compartmentalization and Dynamics of Nuclear Functions team led by Angela Taddei at Institut Curie (https://curie.fr/equipe/taddei). Our research focuses on understanding how nuclear organization regulates genome functions, with a particular emphasis on homologous recombination. We combine state-of-the-art in vivo quantitative microscopy approaches, including super-resolution imaging, with genetic and molecular biology techniques.

The project

This position is part of a project aimed at studying the various stages of the DNA damage response (DDR) in relation to genome spatial organization in the yeast S. cerevisiae.

The missions :

The recruited engineer will have two main responsabilities :

• The individual will strengthen the team’s capacity to generate new yeast strains required for the project’s progress (tool construction : plasmids and strains)
• He/she will adapt the oligopaint tcehnique to vizualize 3D chromosome conformation during the DNA damage response. This part of the project will be carried out with the assistance of a reserach engineer from the Taddei team and a research engineer from the Curie Coretech platform.

As part of his duties, the engineer will conduct experiments, analyzeresults, maintain an up-to-date electronic laboratory notebook, and present project progress at laboratory meetings.

Candidate Profile

Education and experience

• Professional Bachelor’s degree or Master 2
• Experience in molecular biology and microscopy

Required skills and qualities

• Theoretical and practical knowledge of standard techniques in molecular biology (PCR, cloning, probe labeling) and cell biology (immunostaining, fluorescence microscopy).
• Familiarity with image acquisition and analysis software (Metamorph, Fiji).
• Ability to analyze results and synthesize information.
• Good interpersonal skills and ability to work in a team.
• Strong motivation to learn interdisciplinary techniques and work in a collaborative environment.
• Proficiency in English is required, as it is the laboratory’s working language.

Contract information

Type of contract: Fixed-term contract.

Starting date: Position available immediately

Duration: 9 months

Working time: full time

Remuneration: according to the current grids

Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position: Paris

Contact

Please send your CV and letter of motivation: job-ref-jcux61tp2b@emploi.beetween.com

Publication date: 22/07/2026

Deadline for application: until filled

Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.

Where to apply

E-mail: job-ref-jcux61tp2b@emploi.beetween.com

Requirements

• Research Field: Medical sciences » Cancer research
• Education Level: Master Degree or equivalent
• Languages: ENGLISH - Excellent
• Languages: FRENCH - Excellent
• Years of Research Experience: 1 - 4

Work Location(s)

• Number of offers available: 1
• Company/Institute: Institut Curie - Centre de recherche
• Country: France
• City: Ville de Paris, Île-de-France, France
• Postal Code: 75005
• Street: 26 rue d'Ulm

Contact

• State/Province: 160013
• City: Paris
• Website: http://curie.fr/?prehome=0
• Street: 26 rue d'Ulm
• Postal Code: 75005
• E-Mail: job-ref-jcux61tp2b@emploi.beetween.com
• Phone: 0156246527