Job Details
Screen reader users may encounter difficulty with this site. For assistance with applying, please contact [contact details available in the full listing]. If you have questions while submitting an application, please review these frequently asked questions.
Current Employees and Students: If you are currently employed or enrolled as a student at The Ohio State University, please log in to Workday to use the internal application process.
Welcome to The Ohio State University's career site. We invite you to apply to positions of interest. In order to ensure your application is complete, you must complete the following:
- Ensure you have all necessary documents available when starting the application process. You can review the additional job description section on postings for documents that may be required.
- Prior to submitting your application, please review and update (if necessary) the information in your candidate profile as it will transfer to your application.
Job Title: Post Doctoral Scholar - Physiology & Cell Biology
Department: Medicine | Physiology and Cell Biology
The Neginskaya Laboratory in the Department of Physiology and Cell Biology at The Ohio State University invites applications for a Postdoctoral Scholar position to investigate the molecular mechanisms of mitochondrial permeability transition. Mitochondrial permeability transition is a stress-induced increase in the permeability of the inner mitochondrial membrane that contributes to cell death and tissue injury in cardiovascular, neurological, and other diseases.
Current projects focus on the structural organization of mitochondrial membrane protein complexes under stress, the molecular mechanisms underlying mitochondrial permeability transition, and the signaling pathways that regulate mitochondrial dysfunction. The laboratory employs an interdisciplinary approach that integrates mitochondrial patch-clamp electrophysiology, advanced live-cell and label-free imaging, structural biology (cryo-electron tomography and cross-linking mass spectrometry), and biochemical and molecular approaches.
The Postdoctoral Scholar will pursue specialized research training, education, and experience under the guidance of Dr. Neginskaya; plan, design, and execute experiments of considerable scope and complexity to investigate the mechanisms and role of mitochondrial dysfunction in ischemia-reperfusion injury in the heart and brain; collect and analyze data for research sponsored by the National Institutes of Health (NIH) and other funding agencies; identify and investigate significant research questions; develop and troubleshoot new experimental techniques and protocols; attend research seminars; contribute to manuscript preparation and scientific writing; and participate in the preparation of grant applications for extramural funding.
Minimum Education and Skills/Experience Required/Desired
A PhD in biochemistry, cell biology, biophysics, physiology, or a related field is required, along with a strong publication record, the ability to work independently and collaboratively, and excellent written and verbal communication skills. Candidates should have experience in one or more of the following areas: mitochondrial biology, membrane protein biochemistry, electrophysiology, live-cell microscopy, cryo-electron microscopy (cryo-EM) or cryo-electron tomography (cryo-ET), structural biology, quantitative image analysis, mouse models, or bioenergetics.
Our laboratory places a strong emphasis on scientific integrity, transparency, and ethical conduct. We seek team members who value honesty, take ownership of their work, and contribute to a supportive and respectful research environment.
The successful candidate will have the opportunity to develop independent research projects, learn unique experimental approaches, contribute to interdisciplinary studies of mitochondrial biology, and present their work at national and international scientific conferences.
Additional Information
Location: Graves Hall (0277)
Position Type: Term (Fixed Term)
Scheduled Hours: 40
Shift: Varying Shifts
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
Thank you for your interest in positions at The Ohio State University and Wexner Medical Center. Once you have applied, the most updated information on the status of your application can be found by visiting the Candidate Home section of this site. Please view your submitted applications by logging in and reviewing your status. For answers to additional questions please review the frequently asked questions.
The university is an equal opportunity employer, including veterans and disability.