Postdoctoral Associate - Nucleic Acid Delivery

mRNA, siRNA, CRISPR-Cas RNPs, DNA). Postdoctoral Associate will design, formulate, and characterize LNPs; optimize delivery to target cells; and evaluate therapeutic efficacy in relevant in vitro and in vivo models. Job Duties Works on projects under the direction of principal investigator (PI). Helps in setting research directions on a daily basis within projects. Performs experiments and data analysis. Reports data and progresses at weekly meetings with PI and research group. Prepares manuscripts for peer-reviewed publications and provides support for fundraising efforts. Designs, optimizes, and scales lipid nanoparticle formulations. Refines lipid composition for specific payloads and targeted delivery. Performs physicochemical characterization. Tests transfection/knockdown/editing performance in relevant cell systems. Conducts in vivo biodistribution, PK/PD, and safety/toxicity studies. Probes endosomal escape, intracellular trafficking, structure-activity relationships, and uses omics/imaging tools to identify delivery barriers and off‑target effects. Performs other job-related duties as assigned. Minimum Qualifications MD or Ph.D. in Basic Science, Health Science, or a related field. No experience required. Preferred Qualifications Ph.D. degree in pharmaceutical sciences, bioengineering, biomedical engineering, chemical engineering, material science, chemistry or related field. Experience in nanoparticle or LNP formulation and characterization, ionizable lipid chemistry, nucleic acid delivery is highly desirable. Experience in cell culture and molecular assays, flow cytometry and multi-omics is a plus. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.