Postdoctoral Research Scientist (Epigenetics)

We are seeking a Postdoctoral Research Scientist to join the Houseley group at the Babraham Institute, Cambridge to work on metabolic and genetic dysregulation in ageing.

This post addresses the fundamental mechanisms of ageing, focusing on the ageing genome and epigenome. We have recently demonstrated that rewiring of acetyl coenzyme A metabolism, which is critical for epigenetic state and DNA repair as well as fatty acid provision, allows yeast cells to maintain full fitness to the end of life. Excitingly, this rewiring involves highly conserved pathways and we now have both mouse mutants and human ESC cells ready to test how equivalent metabolic changes influence ageing and response to diet in mammals. Analysing these mutants will be the initial aim for this PDRA position, utilising a wide variety of molecular methods, with a particular focus on sequencing methods in which we have a particular specialisation.

This position would suit a candidate with a background in mechanistic studies of metabolism, epigenetics or DNA biology and experience with using mice as a model system. Experience in analysis of high throughput data would be a major advantage and a keen interest in ageing research will be vital.

In addition to the research role the successful applicant will assist the group leader in lab management and student supervision.

This is a 3-year appointment in the first instance but with the potential to become open-ended if successful.

Informal enquiries can be addressed to Dr Houseley (jon.houseley@babraham.ac.uk).

For more information on the work of the group, please visit: https://www.babraham.ac.uk/our-research/epigenetics/jon-houseley

Applicants must hold a PhD or have their thesis submitted when commencing the post. Please note that you will be appointed on the starting salary of £34,500 per annum, if you have not yet been awarded your PhD. All newly appointed postdocs will commence on the salary/scale point that reflects the number of years' post-PhD experience they hold on 30th June in the calendar year they commence employment.

Closing date for applications is Tuesday, 10th February 2026.

However, we reserve the right to close the vacancy early depending on the volume of applications received.

For further details about this position or to apply online please click on the 'Apply' button above.