Rate My Professor Alexandra Sharland

Key publications from her extensive body of work, which has accumulated over 2,300 citations, include 'The self-peptide repertoire plays a critical role in transplant tolerance induction' (Journal of Clinical Investigation, 2021), 'Screening self-peptides for recognition by mouse alloreactive CD8+ T cells using direct ex vivo multimer staining' (Star Protocols, 2023), 'Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells' (Frontiers in Transplantation, 2025), 'Sequestration of tissue-resident alloreactive T cells after intrahepatic activation contributes to tolerance induction' (2024), 'Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4CD25 Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor' (2021), and 'Are Induced/altered Self-peptide Antigens Responsible for De Novo Autoreactivity in Transplantation?' (2023). Recent contributions extend to clinically relevant mouse models for reduced-intensity conditioning in allogeneic hematopoietic stem cell transplantation (2025) and investigations into ischaemic endothelial necroptosis in COVID-19 angiopathy (2025). Her studies have pinpointed molecular targets for transplant rejection monitoring and advanced understanding of immune responses in organ transplantation.