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Andrew L. Goodman, PhD, is the C.N.H. Long Professor of Microbial Pathogenesis and Chair of the Department of Microbial Pathogenesis at Yale School of Medicine, as well as Director of the Yale Microbial Sciences Institute. He received his BA in Ecology and Evolutionary Biology from Princeton University in 1999, his PhD in Microbiology and Molecular Genetics from Harvard University in 2006, and completed postdoctoral training at Washington University School of Medicine in 2010.
Goodman’s research focuses on the mechanisms by which gut microbes interact with their hosts during health and disease, including how the microbiome influences the efficacy and toxicity of medical drugs. His laboratory employs microbial genetics, gnotobiotics, and mass spectrometry to investigate these interactions and has developed innovative tools such as transposon insertion sequencing for studying commensal fitness in the gut. Key publications include studies on microbiome drug metabolism published in Nature and Science in 2019, as well as work on commensal resilience during inflammation in Science in 2015. His contributions have been recognized with awards including the NIH Director’s New Innovator Award, the Pew Charitable Trusts Innovation Fund Award, the Dupont Young Professors Award, the Burroughs Wellcome Foundation award, the Howard Hughes Medical Institute Faculty Scholars Program, the ASPET John J. Abel Award, the Presidential Early Career Award in Science and Engineering, and election as a Fellow of the American Academy of Microbiology in 2022. Goodman has held his current leadership roles at Yale since 2023.
Explore Yale School of Medicine's discovery that COMT inhibitors disrupt gut bacteria, reducing levodopa efficacy in Parkinson's patients. Implications for U.S. university research.
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