Rate My Professor Craig Hutton

Professor Hutton's primary research interest is peptide chemistry, encompassing synthetic organic chemistry, peptide natural products, synthesis, and reaction development. The Hutton Group's expertise lies in amino acid, peptide, and protein chemistry, with projects focused on exploiting thioamide reactivity in peptide synthesis and functionalisation, radiolabelled amino acids and peptides for PET imaging of cancer, biologically active cyclic peptide natural products, cross-linked tyrosine derivatives in peptides and proteins, and organoboron chemistry. He has received Australian Research Council funding for initiatives such as New Synthetic Strategies to Small Cyclic Peptides, A New Direction in Peptide Synthesis: An N-to-C Approach Using Thioamides, and Biogenesis Inspired Total Synthesis of Natural Products. Key publications include Depsipeptide synthesis using a late-stage Ag(i)-promoted macrolactonisation of peptide-thioamides, Late-Stage Pd(II)-Catalyzed C(sp3)−H Functionalization of Peptides Directed by a Removable Backbone-Inserted Amidoxime Ether, Site Specific Preparation of N‐Glycosylated Peptides, and Introduction, Interconversion and Removal of Boron Protecting Groups. In 2022, he was awarded the Dean's Award for Graduate Research Supervision in Chemistry. Professor Hutton has presented seminars on thioamide reactivity in peptide synthesis at conferences including the American Peptide Society meeting and the 16th Australian Peptide Conference.