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Ratings & reviews

4.08/20/2025

Inspires students to love learning.

4.05/21/2025

Fosters collaboration and teamwork.

5.03/31/2025

A true inspiration to all learners.

4.02/27/2025

Creates dynamic and thought-provoking lessons.

4.02/27/2025

Brings enthusiasm and expertise to class.

5.02/4/2025

Great Professor!

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About David

Associate Professor David Stroud serves as an NHMRC Investigator Fellow and head of the Stroud Laboratory for Rare Disease Functional Genomics within the Department of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne. Located at the Bio21 Molecular Science and Biotechnology Institute, his research addresses the challenge of diagnosing monogenic rare diseases, which impact over 7,000 conditions affecting approximately 8% of Australians. The laboratory develops and translates mass-spectrometry-based proteomics technologies to confirm pathogenic genetic variants identified through genomic sequencing, particularly in mitochondrial diseases where genetic heterogeneity complicates diagnosis. This approach has enabled the molecular diagnosis of over 30 individuals with confirmed rare monogenic diseases to date. Key research themes include mass-spectrometry functional testing to boost diagnostic yields, CRISPR/Cas9 gene-edited cell models to validate variant pathogenicity and explore disease mechanisms in multi-protein complexes, and integrative multi-omics analyses encompassing proteomics, transcriptomics, lipidomics, and metabolomics to dissect mitochondrial roles in pathology and devise novel diagnostics. Supported by the Mito Foundation, these efforts aim to standardize tests as NATA/RCPA-accredited clinical genetic pathology services.