Rate My Professor Guo-Jun Liu

Professor Liu's academic interests center on the impact and mechanisms of ionising radiation exposure on healthy brain tissue and brain diseases, with a focus on low-dose radiation effects. His research specializations include the biology of microglia, the 18 kDa translocator protein (TSPO), neuroinflammation, neuropathology, cognitive deficits, glial activation, chemotaxis, mitochondrial bioenergetics, and cell metabolism. Key publications are 'TSPO contributes to neuropathology and cognitive deficits in the 5xFAD mouse model of Alzheimer's disease' (2025), 'Early Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer’s disease' (2025, Nature Communications), 'The 18 kDa Translocator Protein, Microglia and Neuroinflammation' (2014, Brain Pathology), 'Positron emission tomography and functional characterization of a complete PBR/TSPO knockout' (2014, Nature Communications), 'Functional gains in energy and cell metabolism after TSPO gene insertion' (2017, Cell Cycle), 'Glutamate induces directed chemotaxis of microglia' (2009, European Journal of Neuroscience), and 'Guwiyang Wurra – 'Fire Mouse': a global gene knockout model for TSPO/PBR drug development' (2015). These works advance understanding of neuroimmune mechanisms and therapeutic targets in neurodegenerative conditions.