Rate My Professor Jörg Menche

Menche’s research focuses on network medicine and computational biology, leveraging complex network theory to investigate biological systems. His group explores interactome-based approaches to rare diseases, multilayer networks for time- and tissue-specific developmental and aging processes, ubiquitin E3 ligases in cancer, radiomics for clinical applications in liver disease, and genomic stability mechanisms. With over 75 peer-reviewed publications, notable recent contributions include “Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity” (Nature Communications, 2026), “Radiomics-Based Assessment of Portal Hypertension Severity and Risk Stratification of Cirrhotic Patients Using Routine CT Scans” (Liver International, 2026), and “A multilayer network approach elucidates time- and tissue-specific developmental and aging processes” (bioRxiv, 2025). He led the FWF-funded project “Network Medicine - An interactome-based approach to rare diseases” (2016-2024). Menche has received several awards, including the 2019 Falling Walls Lab Austria competition victory (with Julia Pazmandi), Future Innovator recognition at the Ars Electronica Festival 2019, full membership in the Wolfgang Pauli Institute since 2019, and the 2010 best PhD thesis award from the Association of Friends of Colloids and Interface Research.