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Lik-Wei Wong is a Lecturer in the Department of Physiology at the Yong Loo Lin School of Medicine, National University of Singapore (NUS). He holds a PhD from the University of Melbourne and serves in an educator-track role focused on teaching and research in physiology. His academic work centers on the science of learning and memory, with particular emphasis on synaptic plasticity in the hippocampus, the effects of aging, sleep deprivation, and neurodegenerative conditions on these processes, as well as the role of neurotrophin receptors such as p75 NTR in mediating synaptic changes and memory functions.
Wong has contributed to the field through publications including studies on age-related alterations in hippocampal-dependent synaptic plasticity and memory mediated by the p75 neurotrophin receptor (2021), the influence of the p75 neurotrophin receptor on mTOR signaling and synaptic plasticity (2019), and investigations into how caffeine can reverse sleep deprivation-induced deficits in synaptic plasticity and memory (2026). He has received the Faculty Teaching Excellence Award (Individual) from NUS and the Asia Pacific Medical Education Conference (APMEC) 2023 Free Communications Merit Award. Wong is also involved in educational initiatives, such as co-creating knowledge-building activities with learners.
Explore the NUS Medicine study showing caffeine repairs social memory circuits damaged by sleep loss, targeting hippocampal CA2. Implications for students and researchers in Singapore.
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