Rate My Professor Marc Busch

Busch's research interests center on virology, particularly the restrictions in influenza A virus replication, including infectivity phenotypes in primary swine and human respiratory epithelial cells, glycan analysis, hemagglutinin determinants, and interactions between viral nucleoproteins and human host proteins. Notable publications include "Infectivity phenotypes of H3N2 influenza A viruses in primary swine respiratory epithelial cells are controlled by sialic acid binding" (2012), "Identification of putative interactions between swine and human influenza A virus nucleoprotein and human host proteins" (2014), "Amino Acid 226 in the Hemagglutinin of H4N6 Influenza Virus Determines Binding Affinity for 2,6-Linked Sialic Acid and Infectivity Levels in Primary Swine and Human Respiratory Epithelial Cells" (2008), and "Glycan Analysis and Influenza A Virus Infection of Primary Swine Respiratory Epithelial Cells" (2010). In 2019, Busch and Dr. Brian Gentry were awarded a multi-year $390,000 grant from the Merck Investigator Studies Program to investigate letermovir, an antiviral drug targeting the viral terminase enzyme in immunocompromised patients. Busch teaches Cell Biology (BIO 165), Molecular Biology (BIO 186), Cell and Molecular Biology Lab (BIO 187L), Genetics (BIO 105), and Virology (BIO 104).