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Shinji Deguchi serves as Professor in the Division of Bioengineering, Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science at The University of Osaka. He concurrently holds positions as Associate Center Director (Professor) at the Global Center for Medical Engineering and Informatics and at the R3 Institute for Newly-Emerging Science Design. Deguchi earned his Ph.D. from the Graduate School of Engineering at Tohoku University. His prior appointments include roles at Nagoya Institute of Technology from 2013 to 2016, multiple positions at Tohoku University from 2007 to 2013, and Okayama University from 2004 to 2007. He joined The University of Osaka as Professor in 2016.
Deguchi leads the Molecular BioMeasurement Group and conducts research in biomedical engineering and machine materials and mechanics, with emphasis on cellular mechanics, traction force measurement, stress fiber dynamics, actin cytoskeleton behavior, mechanobiology, and related biophysical techniques such as fluorescence recovery after photobleaching. He has received multiple honors, including the 2025 Osaka University Award in the education contribution category and the 2024 Osaka University Award in the university operations category, along with Japan Society of Mechanical Engineers paper awards and the JSME Bioengineering Division Seguchi Award. Deguchi maintains an active publication record with works on topics including cellular homeostatic tension, intracellular dynamics mapping, and adaptive cellular responses.
Osaka University researchers discover AP2A1 protein as 'off switch' for cellular aging, reversing senescence via stress fiber modulation. Explore implications for longevity.
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